IgG4Related Sclerosing Disease

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IgG4-related sclerosing disease.

Based on histological and immunohistochemical examination of various organs of patients with autoimmune pancreatitis (AIP), a novel clinicopathological entity of IgG4-related sclerosing disease has been proposed. This is a systemic disease that is characterized by extensive IgG4-positive plasma cells and T-lymphocyte infiltration of various organs. Clinical manifestations are apparent in the pa...

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Introduction. Sclerosing cholangitis is characterized by an inflammatory and fibrotic lesion of intra- and/or extrahepatic bile ducts. When a causal mechanism of a bile duct lesion is identified, the sclerosing cholangitis is considered secondary. The vasculitis, including the Behçet disease, is cited as a probable cause of the ischemia and the sclerosing cholangitis. No cases of extrahepatic s...

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IgG 4 - related sclerosing disease

Based on histological and immunohistochemical examination of various organs of patients with autoimmune pancreatitis (AIP), a novel clinicopathological entity of IgG4-related sclerosing disease has been proposed. This is a systemic disease that is characterized by extensive IgG4-positive plasma cells and T-lymphocyte infiltration of various organs. Clinical manifestations are apparent in the pa...

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Primary sclerosing cholangitis as an intractable disease.

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A 54-year-old Caucasian woman was admitted due to persistent febrile syndrome, sweating and abdominal pain. Fever marked the onset of the patient’s medical history 10 years earlier. The physical examination revealed normal findings. Laboratory data showed normal white blood cell count, mild microcytic anaemia with a normal reticulocyte count, important inflammatory syndrome (C-reactive protein ...

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ژورنال

عنوان ژورنال: Internal Medicine

سال: 2006

ISSN: 0918-2918,1349-7235

DOI: 10.2169/internalmedicine.45.0137